asterisk users - May 2006 - Virtual VOIP numbers going to separate Asterisk mailboxes?

I use Voicepulse as a VIOP provider, the line comes in via a Sipura
3002 box. That's connected  to the Asterisk box via a TDM422B POTS
card.

I'd like to add a virtual phone number to my VOIP service so that I
can direct calls to a home business to a different voice mail than
calls to the home phone number.

Is there a way for Asterisk to know which virtual number was dialed
under this configuration?

Thanks for any ideas or pointers!