wine users - Jun 2008 - bizarre report of FlashGot firefox 3 extension starting Wine...

http://tech-blog.dinotools.de/2008/06/26/warum-startet-firefox-unter-linux-wine
says that after upgrading to firefox 3 on linux,
starting firefox would briefly open and close "a wine window",
and that it was triggered by the FlashGot extension if
FlashGot Options -> Advanced -> Automatic download manager detection
is enabled.

Whacky.  I haven't tried it myself.