similar to: Problems with nlme: Quinidine example

Dear friends of nlme, Running quinModel (Pinheiro/Bates page 380) on R (current release, windows) gives: Nonlinear mixed-effects model fit by maximum likelihood Model: conc ~ quinModel(Subject, time, conc, dose, interval, lV, lKa, lCl) Data: Quinidine Log-likelihood: -497 Fixed: lV + lKa + lCl ~ 1 lV lKa lCl 5.382 -0.273 2.470 Random effects: Formula: list(lV ~ 1, lCl ~ 1)

Dear listers, I am trying to fit a model using nlsList() using alternately a SSfol() selfstart function or its developped equivalent formulae. This preliminary trial works well mydata<-groupedData(Conc~Tps|Organ,data=mydata) mymod1<-nls(Conc~SSfol(Dose,Tps,lKe,lKa,lCl),data=mydata) as well as a developped form: mymod2<-nls(Conc~Dose * exp(lKe+lKa-lCl) *

Dear list, I do have a problem with nls. I use the following data: >test time conc dose 0.50 5.40 1 0.75 11.10 1 1.00 8.40 1 1.25 13.80 1 1.50 15.50 1 1.75 18.00 1 2.00 17.00 1 2.50 13.90 1 3.00 11.20 1 3.50 9.90 1 4.00 4.70 1 5.00 5.00 1 6.00 1.90 1 7.00 1.90 1 9.00 1.10 1 12.00 0.95 1 14.00

Dear all, I am trying to gain some experience with the function gnls from the nlme package. I tried to model the Theophyline data by trying to model the presumed dependency of the clearance on the body weight. This is my function call of gnls: gnls(conc~SSfol(Dose,Time,lKe,lKa,lCl),data=Theoph, params=list(lKe~1,lKa~1,lCl~Wt),start=c(-2.4,0.46,-3.22,0.01)) That's been the result: Error

library(nlme) data(Phenobarb) na.include <- function(x)x phe1 <- nlme(conc~phenoModel(Subject, time, dose, lCl, lV), data = Phenobarb, fixed = lCl+lV~1, random= pdDiag(lCl+lV~1), start = c(-5,0), na.action = na.include, naPattern = ~!is.na(conc)) phe.ranef <- ranef(phe1,augFrame=TRUE) plot(phe.ranef, form=lCl~Wt+ApgarInd) [Error in max(length(x0),

Greetings, I would like to use a cubic spline or smoother to model the fixed effects within nlme. So far the only smoother I have been able to get to run successfully in nlme is smooth(). I tried smooth.spline: fixed=list(lKa~1,lCL~smooth.spline(BSA, df=3)) the error I got was the following. Error in model.frame(formula, rownames, variables, varnames, extras, extranames, : invalid

A couple of weeks ago there was a question regarding apparent convergence in nls when using the SSfol selfStart model for fitting a first-order pharmacokinetic model. I can't manage to find the original message either in my archive or in the list archives but the data were time conc dose 0.50 5.40 1 0.75 11.10 1 1.00 8.40 1 1.25 13.80 1 1.50 15.50 1

Hello all. I'm having a problem debugging an IVR I'm building. I can't see any reason this shouldn't be working. Firstly the asterisk version is: Asterisk SVN-trunk-r7230 built by root @ localhost.localdomain on a i686 running Linux on 2006-02-17 22:44:48 UTC Basically the problem is this. While the playbacks are happening you can push any one of the options and to happily

Hi, I just wonder if R is still used for PK analysis. However, I have to use R for some purposes anyways. Here is a really strange problem I am running into and I hope to get some assistance from the group. The following code works fine in S-Plus (Population estimates and MAP estimates look reasonable ). cs.fit<-nlme ( CONC~phenoModel(CID,TIME, DOSE, lCl, lV), fixed = lCl+lV ~1,

I'm working on an IVR that gives the users the option (number 5 in the main menu) to dial by extension: exten => 5,1,Set(TIMEOUT(digit)=5) ; Dial Extension exten => 5,2,Set(TIMEOUT(response)=10) exten => 5,3,Background(LCL/prompt-60) exten => 5,4,WaitExten(15) When going option 5 you can dial some extensions such as 2802, it goes to the extension (all extens start with 28 on the

I cannot add users to my server and after going through many google searches and trying several things here is an issue I have found at minimum a LDAP issue when comparing my primary and secondary domain controllers. I do not know how to repair it and that is why I am contacting the list. Below is the output of the comparison. Master: 4.2.0pre1-GIT-58865d9 Slave: 4.2.0pre1-GIT-815bde2 Thank

Hi, I wonder if anybody could help me in converting this easy SAS program into R. (I'm still trying to do that!) PROC IMPORT OUT= WORK.CHLA_italian DATAFILE= "C:\Documents and Settings\carleal\My Documents\REBECCA\stat\sas\All&nutrients.xls" DBMS=EXCEL2000 REPLACE; GETNAMES=YES; RUN; data chla_italian; set chla_italian;

Using samba 3.05 I'm trying to upload printer drivers for point and print using an xp client and I'm getting an error. Unable to install driver ...... Operation could not be completed. I've followed the Samba How To [global] workgroup = local server string = CH File/Print Server passdb backend = ldapsam:ldap://ldap.mycompany.lcl log file =

I have moved to 4.1.16 on both controllers. It did not solve my issue (though it reduced the errors as seen in the new attached ldap comparison). I am still getting the error telling me to see the administrator when trying to add a user via the Windows Active Directory Users and Computers utility. Gilbert [root at pdc ~]# /usr/local/samba/bin/samba-tool ldapcmp ldap://pdc ldap://sdc domain

Hi Gents, I need to get the control limits from qcc function. As follows: qcc(MDI, type = "xbar.one") Call: qcc(data = MDI, type = "xbar.one") xbar.one chart for MDI Summary of group statistics: Min. 1st Qu. Median Mean 3rd Qu. Max. 0.3266 0.4249 0.4371 0.4333 0.4451 0.4858 Group sample size: 1 Number of groups: 383 Center

hello, please can anyone help me out. Am a new user of R program. Am having problem with this code below, not getting the expected results. 1. Each m, the cumulative sum should be 1.000 but the 2nd and 3rd m returned 2.000 and 3.000 instead of 1.000. 2. to get the LCL(m) and UCL(m) for each m base on these instructions if out.cum > 0.025 then LCL(m)= y-1 if out.cum >0.975

If this is off topic I apologize in advance. Using Samba 3.0.13 with an LDAP back-end and FreeRadius I was trying to add the Radius schema and kept getting object class violations. It's my limited understanding of LDAP that you can not have more than one structural objectclass. I'm no ldap expert so no email telling me how wrong I am. So I came up with a another solution. Using the

Folks I have modified an existing function to calculate 'ec/ld/lc' 50 values and their associated Fieller's confidence limits. It is based on EC50.calc (writtien by John Bailer) - but also borrows from the dose.p (MASS) function. My goal was to make the original EC50.calc function flexible with respect to 1) probability at which to calculate the expected dose, and 2) the link

Hello again I'm trying to put error bars onto a barplot. I've tried something that Bill Simpson suggested a while ago, ie: x<-c(1,2,3,4,5) y<-c(1.1, 2.3, 3.0, 3.9, 5.1) ucl<-c(1.3, 2.4, 3.5, 4.1, 5.3) lcl<-c(.9, 1.8, 2.7, 3.8, 5.0) plot(x,y, ylim=range(c(lcl,ucl))) arrows(x,ucl,x,lcl,length=.05,angle=90,code=3) #or segments(x,ucl,x,lcl) but I can't get it to work on a

Hello guys, I got a few questions about winbind / samba and multi domain authentication. At my company we have to different domains. DOMAIN-A and DOMAIN-B My smb.conf is attached (global section only). My linux server (rhel 5.4 x64) is configured with the security mode "ads" and has been joined to the DOMAIN-A via "net ads join DOMAIN-A -U administrator" I can see the