search for: tumors

Hello, I didn't give enough information when I sent an query before, so I'm trying again with a more detailed explanation: In this data set, each patient has a different number of measured variables (they represent tumors, so some people had 2 tumors, some had 5, etc). The problem I have is that often in later cycles for a patient, tumors that were originally measured are now missing (or a "new" tumor showed up). We assume there are many different reasons for why a tumor would be measured in one cycle and...

Hi, I am trying to plot the following data so that it can be visually represented well. I tried the dotchart but I felt it was too spread out. Then I tried the barplot which is good enough for me. Is there a way to give the labels for the y-axis as in the dot chart? Also, I feel the grey level is confusing, so is there options for designs within the bars? I cannot use color as the journal wants

Dear all, please could you advise me on the following : I've written a R script that reads 3 arguments from the command line, i.e. : " args <- commandArgs(TRUE) TUMOR <- args[1] GERMLINE <- args[2] CHR <- args[3] ". when I submit the R script to a PBS HPC scheduler, I do the following (below), but ... I am getting an error message. (I am not posting the error message,

Hi, The problem is most likely, you need to call a R CMD BATCH with your arguments and the R-script inside of a shell script that you submit to your qsub. Unfortunately we don't use qsub anymore so can't test it, but it should be as follows: R-script eg. test.R: > ##First read in the arguments listed at the command line > args=(commandArgs(TRUE)) > > ##args is now a list of

Hi all, I got one problem with comparing strings like if any string is like "*RIGHT, EPICARDIUM: FOCUS, GRAY-WHITE, SINGLE, APPROX 0.6 CM IN DIAMETER*." and i have to compare "*GRAY-WHITE*" with the above string or otherwise i have to compare " *TUMOR BENIGN*" this string with "*MEDULLRY TUMOR BENIGN,TYP PHEOCHROMOCYTOMA*" i

...ovel anti-cancer drugs, AVEO's Translational Research program utilizes a novel platform combining proprietary, inducible tumor models and bioinformatics approaches to discover, validate and generate therapeutics against molecular targets in oncology. We have generated large populations of tumors that exhibit inter-tumor heterogeneity similar to that seen in human tumor populations. Each tumor has been characterized by microarray, array CGH, histology, key signaling pathways as well as sensitivity to a variety of cancer therapeutics, including AVEO's clinical stage drug candidates. Thi...

This sounds like an operating system specific question, in that "submit the R script to a PBS HPC scheduler" would be the kind of action that would run R with very different environment variables and possibly different access credentials than your usual interactive terminal. A thorough reading of the "Installation and Administration Guide" and some study of your HPC

Hello, Would you tell my how to extract a result from a test - it's justified because I need to run this test many times. Here is an example from authors' test: > library("coin") > lungtumor <- data.frame(dose = rep(c(0, 1, 2), c(40, 50, 48)), tumor = c(rep(c(0, 1), c(38, 2)), rep(c(0, 1), c(43, 7)), rep(c(0, 1), c(33, 15)))) > ca.test<-independence_test(tumor ~

Dear R help, I am having a problem with the Design package and my problem is detailed here. I fit a cox model to my data and validate the Somer's Dxy using the Design package. (Because of computation time problem, i only try 10 bootstrap samples for the time being) This is the model without stratification: > library(Design) >

Dear list, I need to read a big txt file (around 130Mb; 23800 rows and 49 columns) for downstream clustering analysis. I first used "Tumor <- read.table("Tumor.txt",header = TRUE,sep = "\t")" but it took a long time and failed. However, it had no problem if I just put data of 3 columns. Is there any way which can load this big file? Thanks for any suggestions!

Hi, I am having troubles with creating an eSet and would appreciate any help on the following problem. I am trying to create an eSet using the following code pd <- read.table(file="pdata.txt",header =TRUE,row.names=1); colnames(pd) <- c("type","tumor","time","id"); pdN <- list(type =

Dear sir, I am Shibu John from Thrombosis Research Institute India. It is a multidisciplinary organisation concerned with the interrelated problems of thrombosis and atherosclerosis. I was searching for Cochran armitage trend test program in R. Then I had seen your R coding for C-A trend test. I tried that in the R software. But I can?t run the program due the [Error: could not find function

Hello, I am trying to explore a classification with GGobi. I am trying to generate additional data according to the model so I can draw the decision boundaries on the GGobi plot. The problem is that I always get the same error: Error in predict.lda(model,data): wrong number of variables, even if I know that I used the same number of variables for the model generation (6) and for the additional

In the vcdExtra package on R-Forge, I have functions and generic methods for calculating log odds ratios for R x C x strata tables. I'd like to define methods for fitting weighted lm()s to the resulting loddsratio objects, but I'm having problems figuring out how to do this generally. # install.packages("vcdExtra", repos="http://R-Forge.R-Project.org")

Hi, I am new to R and AIC scores but what I get from coxme seems wrong. The AIC score increases as p-values decrease. Since lower AIC scores mean better models and lower p-values mean stronger effects or differences then shouldn't they change in the same direction? I found this happens with the data set rats as well as my own data. Below is the output for two models constructed with the rats

Dear R-enthusiasts, I am trying to do a Cochran-Armitage test for trend in R. After consulting google I found Torsten Hothorn's remark that the 'coin' library could be used. lungtumor <- data.frame(dose = rep(c(0, 1, 2), c(40, 50, 48)), tumor = c(rep(c(0, 1), c(38, 2)), rep(c(0, 1), c(43, 7)),

...e model and calculate the likelihood without the gene. And compare each new likelihood with the likelihood of the original original 10 variable model to get likelihood ratio test for each gene. I guess gene 8 should have best discrimination power because it can totally seperate the two group tumors. But the test result shows the likelihood ratio for Ratio 8 is not the biggest. Where am I wrong? The package is not good for this problem? But the package document says this package takes care of separation and small sample size by finite parameter estimates and profile penalized log likelihoo...

...m looking for some help in making two boxplots next to each other. I have a data like this: N1 T1 N2 T2 N3 T3 N4 T4 ... Nn Tn 7 8.2 4 5 8 10 4 5 ..... 10 11 I want to have box plot for all Normal samples (N1,N2,N3,N4,,,,Nn) and another box plot for all tumors (T1,T2,T3,T4,...Tn). I have data in a numeric class. If data is represented as N1 N2 N3 N4 T1 T2 T3 T4 I can do something like the following: if x object is my data matrix boxplot(x ~ c(rep('N',n),rep('T',n)), ylim=ylim, main=title) since the data is arranged as N1 T1, I don&...

I am interested in plotting histograms for the following data Isoform Tumor_65_198 Tumor_50_192 Tumor_80_167 Tumor_80_204 Tumor_95_197 Tumor_70_189 Tumor_90_202 Tumor_40_177 Tumor_60_21 Tumor_70_174 Tumor_70_147 Tumor_50_5 ABCC4-2007 1 1 1 6 1 9 10 1 2 0 10 1 ABCC4-2008 5 8 7 5 3 10 5 5 7 3 10 3 ABCC4-2009 0 0 0 0 0 0 0 0 0 0 0 0 ABCC4-2010

Hello R users, I am trying to run a cox model for the prediction of relapse of 80 cancer tumors, taking into account the expression of 17000 genes. The data are large and I retrieve an error: "Cannot allocate vector of 2.4 Mb". I increase the memory.limit to 4000 (which is the largest supported by my computer) but I still retrieve the error because of other big variables that I have...