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2010 Dec 09
1
Statistics of count data for differential expression
...e Chip-Seq read count data from a "control / wild type (C)" experiment. I have 3 replicates (2 technical, 1 biological) of each of these. What is the best way to go for a differential expression between T1 and T2? Is it best to just go straight between T1 and T2 or is it to do a T1vsC and T2vsC and then compare the results from these for diff expr? What do you think is better and why? I appreciate your thoughts on this. Sincerely, Vishal [[alternative HTML version deleted]]