search for: reuimplement

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2003 Oct 27
0
Whitehead's group sequential procedures
...lementation of John Whitehead's procedures for the planning and analysis of group sequential clinical trials. His book is enlightenig but somewhat frustrating : it has a good basic exposition of his framework, but the technical details are sparse, and leave much work to do when one plans to reuimplement part of the procedures. For example, one has to work out the computation of test regions in non-trivial cases, the P-value and confidence interval building, etc ... Given my abilities, I'd rather *not* do this ... Did someone implement these procedures in R ? I am aware of a (commercial)...