Displaying 2 results from an estimated 2 matches for "quinmodel".
2001 Feb 04
1
quinModel S != R
Dear friends of nlme,
Running quinModel (Pinheiro/Bates page 380) on R (current release, windows)
gives:
Nonlinear mixed-effects model fit by maximum likelihood
Model: conc ~ quinModel(Subject, time, conc, dose, interval, lV, lKa,
lCl)
Data: Quinidine
Log-likelihood: -497
Fixed: lV + lKa + lCl ~ 1
lV lKa lCl
5.382 -0....
2005 Jul 07
2
Problems with nlme: Quinidine example
This concerns the "Clinical Study of Quinidine" example on page 380
of the book "Mixed-Effects Models in S and S-PLUS" by Pinheiro and Bates (2000).
I have tried to reproduce the example, but get an error:
> library(nlme)
> fm1Quin.nlme <- nlme(conc ~ quinModel(Subject, time, conc, dose, interval, lV,
lKa, lCl),
+ data=Quinidine,
+ fixed=lV + lKa + lCl ~ 1,
+ random=pdDiag(lV + lCl ~ 1),
+ groups= ~ Subject,
+ start=list(fixed=c(5, -0.3, 2)),
+...