Displaying 3 results from an estimated 3 matches for "quinidin".
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quinidine
2005 Jul 07
2
Problems with nlme: Quinidine example
This concerns the "Clinical Study of Quinidine" example on page 380
of the book "Mixed-Effects Models in S and S-PLUS" by Pinheiro and Bates (2000).
I have tried to reproduce the example, but get an error:
> library(nlme)
> fm1Quin.nlme <- nlme(conc ~ quinModel(Subject, time, conc, dose, interval, lV,
lKa, lCl),
+...
2001 Feb 04
1
quinModel S != R
Dear friends of nlme,
Running quinModel (Pinheiro/Bates page 380) on R (current release, windows)
gives:
Nonlinear mixed-effects model fit by maximum likelihood
Model: conc ~ quinModel(Subject, time, conc, dose, interval, lV, lKa,
lCl)
Data: Quinidine
Log-likelihood: -497
Fixed: lV + lKa + lCl ~ 1
lV lKa lCl
5.382 -0.273 2.470
Random effects:
Formula: list(lV ~ 1, lCl ~ 1)
Level: Subject
Structure: Diagonal
lV lCl Residual
StdDev: 4.43e-12 0.321 0.76
lV is confusing, since the book examples says it shou...
2004 Dec 19
1
PBIB datataset
I'm looking at Pinheiro & Bates "Mixed-Effects Models in
S and S-PLUS" at the moment. Several datasets are used,
one of which is called "PBIB" (a partially balanced
incomplete block design).
All the other datasets can be found somewhere or other in R.
However, I cannot locate PBIB, and it does not seem to
be mentioned in the latest edition of the R Full Reference