search for: omic

...therdevelopment of biomarkers. The chosen candidate will be part of ourmultidisciplinary team conducting studies to discover and developdiagnostic biomarkers as well as biomarkers for the characterization ofdisease models and drug effects ? including side effects. Essential functions * Analyzing omics data and integration of Metabolomics with other omics data-selection of likely metabolite, protein and RNA targets for quantification. * Providing software support for team members. * Contributing to presentations, patent applications, scientific publications and reporting on project funding. Re...

...fic Collaborator in Statistical Bioinformatics* *Institute for Medical Informatics, Statistics and Documentation**, Medical University of Graz, Austria* predoc level with PhD opportunity, 30 hours per week available from May 1st, 2012 *Tasks:* * Working in the project "Biostatistical-genomical analysis of the clinical relevance of liver cancer models" which is collaborative research with the Institute of Pathology and part of international collaborations on metabolic disease-driven hepatocellular cancer * Statistical analysis of human and mouse arrayCGH data from our...

Dear all, we seek a talented and motivated post-doc to develop computational methods for inferring the molecular basis of genetic diseases by integration of personal omics data. Research topics include: identifying causal mutations of rare disease patients by meta-analysis; inferring disease-causing molecular pathways from genotype, phenotypes, and omics profile of patient-derived cell lines (transcritptomic, proteomic and metabolic). The developed methods will be a...

...Innsbruck, Austria, has an opening for a biostatistician. If you have any interest, feel free to contact me or Dr Markus Speiser (markus.speiser*at*biocrates.com). Best regards, David ################## Biostatistician (m/f) Job Description BIOCRATES Life Sciences AG is a leading metabolomics company using a mass-spectrometry based technology platform. Its products and services extract, deliver, and present rich information residing in metabolite networks with unprecedented speed, low cost, and high reliability. Biocrates? quantitative approach enables immediate identification of metab...

...ests directory) of a package that run routinely as part of "R CMD check" must complete in five minutes. [2] Nontrivial regression testing of complex algorithms on real data can easily take longer than five minutes. [3] Maintaining and improving code that works on various kinds of "omics" data is greatly facilitated by the inclusion of nontrivial regression tests. Of course, points [1] and [3] are incompatible in the current setup. Both could, however, be accommodated by changing the way "R CMD check" runs test scripts. There are at least two ways this could be...

Dear mailing list, Genomics Medicine Ireland is opening new positions for our bioinformatics team. The team will analyse the ?omics data produced at GMI, which currently includes disease cohorts such as IBD, Multiple sclerosis, Alzheimer's, rare diseases, cancer and recently we have opened programs in diabetes and asthma...

...p -v SUNW application SMCbinut binutils application SMCgcc3 gcc application SMClsof lsof application SMCmake make application SMCnmap namp application SMCosslc openssl application SMCsudo sudo $ My path during the build was: $ echo $PATH /lhome/cs71/omichael/bin:/bin:/usr/bin:/usr/sbin:/sbin:/usr/local/bin:/usr/local/sbin $ and with no special LD_LIBRARY_PATH or LD_RUN_PATH. Now, the only problem I had was, that the buildpkg.sh scripts does a ## Extract common info requires for the 'info' part of the package. VERSION=`tail -1 ../../ve...

Hi, I am working on a multivariate linear regression of the form y = Ax. I am seeing a great dispersion of y w.r.t x. For example, the correlations between y and x are very small, even after using some typical transformations like log, power. I tried with simple linear regression, robust regression and ace and avas package in R (or splus). I didn't see an improvement in the fit and

...ent. Role and Responsibilities: The statistician will be an integral member of a systems biology team which develops and/or uses computational and statistical approaches to manage and derive knowledge of biological processes from large biological datasets (e.g., expression profiling, and other ?omics? sets). In this role, he/she will share accountability for achieving team goals focused on: * Drug target discovery * Early biomarker discovery * Pathway understanding and mechanistic insight Teams will consist of computational biologists, geneticists, statisticians and bioinformatics special...

...h.D. in Statistics or Biostatistics, as well as a minimum of two years statistical consulting experience in applying statistics to the understanding of biological problems, preferably in a laboratory science environment. Ideally, this experience would include exposure to the design and analysis of ?omics? data (e.g. gene expression, siRNA, etc.) . Preferred candidates will have strong computational skills in R, S-plus or SAS. In summary, we seek a person with a solid background in experimental statistics and a genuine interest in working to develop medicines for the treatment of neuro/psychiatri...

...tists, engineers, and managers in research, drug discovery, preclinical testing, process and product development, manufacturing, and quality control. Statistical activities are commensurately diverse, including: design and analysis of in vitro and in vivo efficacy, pharmacokinetics, toxicity, and ?-omics? studies; statistical support for assay and manufacturing development and characterization; and support for regulatory activities for marketed products. We seek individuals with a broad knowledge of statistical methodology to work in a collaborative, team-oriented, science-driven environment. Fo...

...more details see the corresponding NEWS files (e.g. news(package = "RobAStBase") or using function NEWS from package startupmsg i.e. NEWS("RobAStBase")). First of all the new package RobLoxBioC was added to the family which includes S4 classes and methods for preprocessing omics data, in particular gene expression data. ############################################## ## All packages (RandVar, RobAStBase, RobLox, RobLoxBioC, ## ROptEst, ROptEstOld, ROptRegTS, RobRex) ############################################## - TOBEDONE file was added as a sta...

> Toxicogenomics Statistician > > The successful candidate will provide statistical support to nonclinical > areas of R&D, especially in the areas of investigative toxicology, safety > biomarkers, and toxicogenomics. The candidate will collaborate with > scientists to plan meaningful experimen...

...more details see the corresponding NEWS files (e.g. news(package = "RobAStBase") or using function NEWS from package startupmsg i.e. NEWS("RobAStBase")). First of all the new package RobLoxBioC was added to the family which includes S4 classes and methods for preprocessing omics data, in particular gene expression data. ############################################## ## All packages (RandVar, RobAStBase, RobLox, RobLoxBioC, ## ROptEst, ROptEstOld, ROptRegTS, RobRex) ############################################## - TOBEDONE file was added as a sta...

Hello, everyone! I have a set of proteomic data .And I do a solexa sequencing in the corresponding sample. So I get much mass sequencing data. How can I using R to integrate those two set data. I wonder if some tool or R package would help me? Thank you ! [[alternative HTML version deleted]]

...ncology. You will provide biostatistical expertise to the Core and contribute to the design of studies, the analysis of data and the development of new analytical methods. This position will involve various aspects of statistics from biostatistics and statistical genetics to the integration of *omics data, under the supervision of senior members of the Bioinformatics Core: Dr Jean-Baptiste Cazier, Group Leader, and Francesca Buffa, Clinical Genomics Lead. It includes provision of design and analysis as well as development of novel statistical approaches to solve problems specific to the D...

Dear all, please could you suggest any R functions or packages (or external programs), that a. take as input a large number (> 10 000) of short 20-30 nt sequences, and do sequence assembly, to reconstruct larger (extended) 30-50 sequences ? b. take as input a larger number of sequences (100 000 - 1 mil) and cluster these sequences in distinct classes based on the sequence similarity ?

...interest in growing both their engineering skills to handle large datasets and bring an entrepreneurial spirit to work on societal data science. The current projects involve: 1. The underlying theme of our computational biology projects is to develop machine learning methods for the mining of big ?omics? data in biology. Our overarching goal is to develop personalized medicine that uses genetic information to tailor therapy for individual patients. Collaboration with an interdisciplinary team (e.g. clinicians and biologists) is an essential component in our projects. 2. Health Care Analytics eff...

...lle et al. (2008) as a dimension reduction method for exploring gene-gene interactions. * minqa (1.1) Katharine Mullen http://crantastic.org/packages/minqa Derivative-free optimization by quadratic approximation based on an interface to Fortran implementations by M. J. D. Powell * mixOmics (2.6) Kim-Anh Le Cao http://crantastic.org/packages/mixOmics The package supplies two efficients methodologies: regularized CCA and sparse PLS to unravel relationships between two heterogeneous data sets of size (nxp) and (nxq) where the p and q variables are measured on the same samp...

Hello, Following a discussion initiated on r-devel, that mentions SciViews-R and other GUIs issues for R, I would like to make comments (and would be happy if these comments would initiate interesting initiatives). A big, big problem with SciViews-R is that a part of it is written in Visual Basic 6, a M$$$$ language, not supported any more, buggy, non transposable to other platforms, etc,