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enlightening
2003 Oct 27
0
Whitehead's group sequential procedures
Dear List,
I would like to know if there exist some R implementation of John
Whitehead's procedures for the planning and analysis of group sequential
clinical trials. His book is enlightenig but somewhat frustrating : it
has a good basic exposition of his framework, but the technical details
are sparse, and leave much work to do when one plans to reuimplement
part of the procedures. For example, one has to work out the computation
of test regions in non-trivial cases, the P-value a...