search for: biomark

One Year Student in Bioinformatics (Biomarkers discovery)-1000435 See following URL for job application: http://www.merckserono.com/en/careers/job_center/job_center.html Description Background: Biomarker discovery is now an intricate part of the drug development process as it will allow for more accurate identification of patients w...

...h reliability. Biocrates? quantitative approach enables immediate identification of metabolites, measurement of their absolute concentrations, and mapping to their respective pathways. We are looking for a PhD holder in Bioinformatics with a minimum of three years working experience to support our biomarker team in the identification, validation and further development of biomarkers. The chosen candidate will be part of our multidisciplinary team conducting studies to discover and develop diagnostic biomarkers, as well as biomarkers for the characterization of disease models and drug effects, includ...

Dear all, The CRUK MI have multiple positions in and around bioinformatics, biostatistics and computational biology. These range from HPC and mathematical programming, through biostatistics and biomarkers, to computational biology and bioinformatics. Focuses include single cell genomics and personalised medicine in lung and prostate cancer. For full details, please visit our website at: http://www.cruk.manchester.ac.uk Brief summaries below: RNA Biology Group - Crispin Miller ================...

Hi, Is there anyone know if BUGS language allows the combination of variables as response such as Y[i] <- a*X1[i]+b*X2[i] Y[i] ~ dnorm(c,d) It seems doesn't work in my model. The problem is between two ######. The error message is > modelCheck("BayesBioMarker.BUGS") model is syntactically correct > modelData(paste("BUGS_data.txt",sep="")) data loaded > modelCompile(numChains=1) multiple definitions of node bm[1] =================================== model { for(iter in 1:numSubj){...

...have rescaled all the variables to be in 0 to 1 range - is this the proper way to go? Is there a way to somehow calculate the same HRs (as for rescaled parameters) from the HRs for original parameters? Many thanks in advance. -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney Philadelphia, PA 19104 tel. (215) 662-3413

...e are seeking a highly motivated, independent bioinformatics scientist to join a group of scientists, analysts and programmers to develop tools and methodologies for large-scale gene expression data analysis. The group supports a variety of research projects in target and drug discovery as well as biomarker development for AVEO's growing pipeline of novel anti-cancer drugs, AVEO's Translational Research program utilizes a novel platform combining proprietary, inducible tumor models and bioinformatics approaches to discover, validate and generate therapeutics against molecular targets in...

We are looking for a MSc or PhD holder in Bioinformatics,Molecular/Computational Biology or Computer Science to support ourbiomarker team in the identification, validation and furtherdevelopment of biomarkers. The chosen candidate will be part of ourmultidisciplinary team conducting studies to discover and developdiagnostic biomarkers as well as biomarkers for the characterization ofdisease models and drug effects ? including...

...ge from "Alexey E. Suslikov" <cruel@texnika.com.ua> ----- Date: Tue, 11 Jan 2005 11:36:08 +0200 From: "Alexey E. Suslikov" <cruel@texnika.com.ua> Subject: Biometric Authentication for BSD/Linux X-Mailer: The Bat! (v3.0.2.4 Rush) Professional Homepage is here http://biomark.org.ru/en/ It is BSD-licensed http://biomark.org.ru/files/license.txt and uses PAM under BSD-systems http://biomark.org.ru/en/software/pam_bfp.html ----- End forwarded message ----- -- Christian Brueffer chris@unixpages.org brueffer@FreeBSD.org GPG Key: http://people.freebsd.org/~brueffer...

...dy of injury induced immunosuppression. This program aims at (i) describing and understanding the mechanisms leading to post-injury immune dysfunctions as well as their association with increased risk of health-care associated infections or fatal outcomes, (ii) identifying and developing innovative biomarkers that could help to monitor immunosuppression and stratify patients in clinical trials. Within this structure, a position funded for 2 years (post-doctoral or equivalent) in bioinformatics and biostatistics is open for recruitment. Job Description Bioinformatics to analyze high-throughput da...

...t NRI or IDI. Can anyone suggest any other packages that can calculate NRI and IDI for survival data? The reference for NRI extending to survival data is: Pencina MJ, D'Agostino RB, Steyerberg EW (2011): Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat in Med 30:11-21 Thanks! John [[alternative HTML version deleted]]

...ut this position please contact Christina Kinchen at ckinchen at smithhanley.com or at 800-684-9921 ext 220. The successful candidates' primary responsibility will be to create a suite of validated, general-purpose programs for conducting pre-processing and statistical analyses of clinical and biomarker data, including large-scale genomic data. In many cases the core statistical methodology has already been implemented for a specific analysis and needs to be generalized, validated, and made more efficient. A secondary responsibility is to assist statisticians in their analyses, including such ta...

...roteinB=rnorm(m=13,s=0.7,n=40)) gls(ProteinB~ProteinA, data=x, corr=corSymm(form=~Visit|Patient.ID) In the results I see correlations between the occasions and between terms, but not between the proteins. Where to look for it? -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney S Philadelphia, PA 19104 tel. (215) 662-3413

Dear Sirs. I am working with the R packages Hmisc and PredictABEL to make NRI estimates from my Cox models with and without a specific biomarker. According to Pencina et al (Statistics in Medicine 2010, DOI: 0.1002/sim.4085 ), a continuous/non-categorical NRI (NRI>0) is to be used when there are no obvious reason to categorize risk, such as the risk of future cardiovascular events in patients with established cardiovascular disease. M...

...en the second produces and error "The system cannot find the path specified." - completely as if the computer has forgotten all the paths and settings from the first call. Does anyone know a solution to this problem? -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney Philadelphia, PA 19104 tel. (215) 662-3413

...print.it = FALSE, times = times) : object 'n.enter' not found" Actually, using 'survest(f, time=3)' has the same result. Has anybody encountered this kind of error? Is there a workaround? Best regards, -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney Philadelphia, PA 19104 tel. (215) 662-3413

...up participant on Clinical Project teams representing clinical programming efforts for that clinical team. -Prefer candidate with clinical experience. -SAS program experience required. Responsibilities: -Contribute to the programming of tables and graphs for various projects related to genomics/biomarkers and discovery, which include in vitro and animal pharmacology. -Help develop automation tools in Microsoft Excel using internal links to Visual Basic, SAS or R; develop SAS macros and R functions for various analysis tasks, with guidance and core code from the statisticians. -SAS and S-Plus/R...

...up participant on Clinical Project teams representing clinical programming efforts for that clinical team. -Prefer candidate with clinical experience. -SAS program experience required. Responsibilities: -Contribute to the programming of tables and graphs for various projects related to genomics/biomarkers and discovery, which include in vitro and animal pharmacology. -Help develop automation tools in Microsoft Excel using internal links to Visual Basic, SAS or R; develop SAS macros and R functions for various analysis tasks, with guidance and core code from the statisticians. -SAS and S-Plus/R...

...rently ignored. I guess this means it's not a trivial thing to do. Does anyone have a suggestion on how to obtain confidence predictions for such a model? Please cc my email address when you reply. Thanks and best regards, -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney Philadelphia, PA 19104 tel. (215) 662-3413

...ing the values fitted by the instrument soft - to no avail. I've probably seen all possible error messages from 'nls' trying to fit this. If anyone has an idea why it's not working - let me know. Best regards, -- Michal J. Figurski, PhD HUP, Pathology & Laboratory Medicine Biomarker Research Laboratory 3400 Spruce St. 7 Maloney S Philadelphia, PA 19104 tel. (215) 662-3413

Dear All, I know how to export graphics as pdf files and then how to include them in LaTeX documents. However, I do not know how to do in order to have the text of the graphics written with the font selected for the LaTeX document. Is that possible? Thanks in advance, Paul