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Hello, I've just a little problem using the function optim. Here is the function I want to optimize : test_function(x){(exp(-0.06751 + 0.25473*((x[1]-350)/150) + 0.04455*((x[2]-40)/20) + 0.09399*((x[3]-400)/100) - 0.17238*((x[4]-250)/50)- 0.45984*((x[5]-550)/150)-0.39508*((x[1]-350)/150)* ((x[1]-350)/150) - 0.05116*((x[2]-40)/20)* ((x[2]-40)/20) - 0.27735*((x[3]-400)/100)*((x[3]-400)/100) -

the study design of the data I have to analyse is simple. There is 1 control group (CTRL) and 2 different treatment groups (TREAT_1 and TREAT_2). The data also includes 2 covariates COV1 and COV2. I have been asked to check if there is a linear or quadratic treatment effect in the data. I created a dummy data set to explain my situation: df1 <- data.frame( Observation =

Dear R-help members, Apologies - I am posting on behalf of a colleague, who is a little puzzled as STATA and R seem to be yielding different survival estimates for the same dataset when treating a variable as ordinal. Ordered() is used to represent an ordinal variable) I understand that R's coxph (by default) uses the Efron approximation, whereas STATA uses (by default) the Breslow. but we