Hugo Pedder
2019-Jul-25 16:40 UTC
[R-pkgs] New package MBNMAdose: dose-response meta-analysis
Hi all, I would like to introduce you to a new package available on CRAN for performing meta-analysis of dose-response relationships, 'MBNMAdose'. For anyone who has performed a meta-analysis or network meta-analysis before, you might be aware of the difficulties of including different doses of a drug. Typically one either assumes that different doses have a broadly similar effect, or that they are totally independent. MBNMAdose allows you to explicitly model the dose-response relationship in a statistically robust framework. By modelling dose-response relationships this can connect networks of evidence that might otherwise be disconnected, and can improve precision on treatment estimates. There's a detailed vignette included with the package that explains everything in a lot more detail for those that are interested. Any feedback or suggestions for improvements would be hugely welcome. Many thanks, Hugo Hugo Pedder Senior Research Associate Population Health Sciences University of Bristol [[alternative HTML version deleted]]