[cross-posted from bioc-devel list] Hi all, I have a subtle question related to how R CMD SHLIB handles variables in make child processes. In more detail: I am the maintainer of the 'msa' package which has been in Bioconductor since April 2015. This package integrates three open-source libraries for multiple sequence alignment. This is organized in the following way: in src/, there are three sub-directories, one for each of the libraries (plus another one for a garbage collector library, but that is not relevant at this point). src/Makevars is made such that the libraries are compiled individually to static libraries in their respective sub-directory, then these static libraries are copied to src/, and finally the static libraries are integrated into msa.so. The Makevars file looks as follows: PKG_LIBS=`${R_HOME}/bin${R_ARCH_BIN}/Rscript -e "if (Sys.info()['sysname'] == 'Darwin') cat('-Wl,-all_load ./libgc.a ./libClustalW.a ./libClustalOmega.a ./libMuscle.a') else cat('-Wl,--whole-archive ./libgc.a ./libClustalW.a ./libClustalOmega.a ./libMuscle.a -Wl,--no-whole-archive')"` PKG_CXXFLAGS=-I"./gc-7.2/include" -I"./Muscle/" -I"./ClustalW/src" -I"./ClustalOmega/src" .PHONY: all mylibs all: $(SHLIB) $(SHLIB): mylibs mylibs: build_gc build_muscle build_clustalw build_clustalomega build_gc: make --file=msaMakefile --directory=gc-7.2 @echo "----------------------------------------" @echo "------------------ GC -----------------" @echo "----------------------------------------" @echo "--------- Compilation finished ---------" @echo "----------------------------------------" build_muscle: make --file=msaMakefile --directory=Muscle @echo "----------------------------------------" @echo "---------------- MUSCLE ----------------" @echo "----------------------------------------" @echo "--------- Compilation finished ---------" @echo "----------------------------------------" build_clustalw: make --file=msaMakefile --directory=ClustalW @echo "----------------------------------------" @echo "--------------- ClustalW ---------------" @echo "----------------------------------------" @echo "--------- Compilation finished ---------" @echo "----------------------------------------" build_clustalomega: make --file=msaMakefile --directory=ClustalOmega @echo "----------------------------------------" @echo "------------- ClustalOmega -------------" @echo "----------------------------------------" @echo "--------- Compilation finished ---------" @echo "----------------------------------------" This has always worked on Linux and Mac OS so far. Now I have received an error report from a user who cannot install the package on a 64-bit openSUSE 13.1 system using R 3.3.1. It turned out that R CMD SHLIB as called in the make child processes (make target 'build_muscle' above) uses the value of PKG_LIBS defined in the first line of the top-level Makevars file shown above (which of course does not work and makes no sense), while this does not happen on any other Unix-like system I have tried so far (Ubuntu, CentOS, Mac OS). Maybe somebody can shed some light on how variables defined inside the Makevars file propagate to child processes. Thanks so much in advance! Best regards, Ulrich