Hi list, I've a problem with my system on CentOS 6.5 x86_64 on a workstation. During utilizzation, after several hours after boot (6/7 hours) I get an error: Disabling IRQ #16 and after this seems be that 3d acceleration is unloaded. This is a workstation with a dedicated vga (nvidia gt450) and 3 nics. This problem started when I've plugged the third nic. Without third nic all works very good. from /proc/interrupt: 16: 110 647 64858 0 0 0 0 0 IO-APIC-fasteoi ehci_hcd:usb1, ahci, eth3, nvidia I've tried to boot the system with irqpool without great results. I've tried to change my new third gb nic with a fast ethernet 10/100, thinking it was broken but the problem still persists. I've tried to replace my vga card with another, the problem still persists. From dmesg I get: Call Trace: <IRQ> [<ffffffff810e8fdb>] ? __report_bad_irq+0x2b/0xa0 [<ffffffff810e91dc>] ? note_interrupt+0x18c/0x1d0 [<ffffffff810e997d>] ? handle_fasteoi_irq+0xcd/0xf0 [<ffffffff8100faf9>] ? handle_irq+0x49/0xa0 [<ffffffff815315fc>] ? do_IRQ+0x6c/0xf0 [<ffffffff8100b9d3>] ? ret_from_intr+0x0/0x11 <EOI> [<ffffffff812e0bee>] ? intel_idle+0xde/0x170 [<ffffffff812e0bd1>] ? intel_idle+0xc1/0x170 [<ffffffff81426b67>] ? cpuidle_idle_call+0xa7/0x140 [<ffffffff81009fc6>] ? cpu_idle+0xb6/0x110 [<ffffffff8152143c>] ? start_secondary+0x2ac/0x2ef handlers: [<ffffffff813c4260>] (usb_hcd_irq+0x0/0x90) [<ffffffffa004d610>] (ahci_interrupt+0x0/0x790 [ahci]) [<ffffffffa00a2740>] (irq_handler+0x0/0x5a0 [firewire_ohci]) [<ffffffffa0bc98f0>] (rtl8169_interrupt+0x0/0x80 [r8169]) [<ffffffffa073e7a0>] (nv_kern_isr+0x0/0x80 [nvidia]) Disabling IRQ #16 I've inserted the third nic for channel bonding. What I can try to avoid this error? It's an hardware problem on mobo? Any hints will be good. Thanks in advance.