similar to: analysis strategy - baseline and repeated measure

Hi all, I asked this before the holiday, didn't get any response. So would like to resend the message, hope to get any fresh attention. Since this is not purely lme technical question, so I also cc-ed R general mailing list, hope to get some suggestions from there as well. I asked some questions on how to analyze longitudinal study with only 2 time points (baseline and a follow-up)

Hi, I am fairly new to R and still trying to figure out how it all works, and I have run into a few issues. I apologize in advance if my questions are a bit basic, I'm also no statistics wizard, so part of my problem my be a more fundamental lack of knowledge in the field. I have a dataset that looks something like this: Week Subj Group Readout 0 1 A 352.2 1 1 A

I came across a post by Karl Knoblick regarding the modeling of longitudinal data (see https://stat.ethz.ch/pipermail/r-help/2007-May/132137.html). I am often asked by physicians to perform what Karl refers to in his post as option 1: to perform paired t-tests against baseline at each follow up time point (30 days, 90 days, 6 months, etc.). Unlike Karl's example, however, many of the trials

Dear, I want to analyze an outcome in an RCT using lme but I am not sure that I have chosen the right way for the model. We measured the outcome three times repeatedly in the same patient. One time before intervention and two times after intervention. I wanted to adjust for the correlated data in the repeated measurement and baseline differences in the variable in order to get the treatment

Hallo! I have data of the following design: NSubj were measured at Baseline (visit 1) and at 3 following time points (visit 2, visit 3, visit 4). There is or is not a treatment. Most interesting is the question if there is a difference in treatment between the results of visit 4 and baseline. (The other time points are also of interest.) The level of significance is alpha=0.0179 (because of an

Hello all, I'm almost embarrassed to post this , it seems so easy. Suppose I have a baseline and follow up survey but some people are missing in the follow up: > baseline<-data.frame(id=c(3,5,7,9,12), data= runif(5)) > follow.up<-data.frame(id=c(3,7,9,12), data= runif(4)) > baseline id data 1 3 0.66771988 2 5 0.28794744 3 7 0.01892821 4 9 0.64863175 5 12 0.86485882

Dear R-help and Prof. Harrell: My question concerns the baseline state for continuous variable in lrm() within the RMS package. I have a model which can be reduced to: lrm(FT ~ rcs(V1, c(0, 1,5)) The model makes perfect sense if the baseline state is where V1>=5 but the model makes no sense if the baseline category is 0 (which I had expected). Can someone point me to a reference, or

Dear R-help, I am trying to obtain the baseline survival estimate of a fitted Cox model (S_0 (t)). I know that previous posts have said use 'basehaz' but this gives the baseline hazard function and not the baseline survival estimate. Is there a way to obtain the baseline survival estimate or do I have to use the formula which does something like S(t) = exp[- the integral from 0 to t of

-------- Original Message -------- Subject: Re: How to obtain nonparametric baseline hazard estimates in the gamma frailty model? Date: Mon, 04 Nov 2013 17:27:04 -0600 From: Terry Therneau <therneau.terry at mayo.edu> To: Y <yuhanusa at gmail.com> The cumulative hazard is just -log(sfit$surv). The hazard is essentially a density estimate, and that is much harder. You'll notice

Dear All, I'm having just a little terminology problem, relating the language used in the Hosmer and Lemeshow text on Applied Survival Analysis to that of the help that comes with the survival package. I am trying to back out the values for the baseline hazard, h_o(t_i), for each event time or observation time. Now survfit(fit)$surv gives me the value of the survival function, S(t_i|X_i,B),

Dear R Masters, I'm an anesthesiology resident trying to make his way through basic statistics. Recently I have been confronted with longitudinal data in a treatment vs. control analysis. My dataframe is in the form of: subj | group | baseline | time | outcome (long) or subj | group | baseline | time1 |...| time6 | (wide) The measured variable is a continuous one. The null hypothesis in

Dear All, I am a researcher doing research in plant growth and I have a statistical problem that seems to not be able to handle. Recently, I conducted an experiment about plant growing in three different nutrient-level sediments. I harvested these every three week (three harvests in all). Some growth traits of these plants were recorded (e.g. total biomass, leaf biomass and stem biomass). In

Hi, I have what I believe is a repeated-measures dataset that I'm trying to analyze using lme(). This is *not* homework, but an exercise in my trying to self-teach myself repeated-measure ANOVA for other *real* datasets that I have and that are extremely similar to the following design. I'm fairly sure the dataset described below would work with lme() -- but it'd be great if anybody

Dear R-help mailing list,   Kindly help me out with this problem:   I have a dataset that is in the format below, ID  time  Y  Age 1  0     195  23.1 1  2    204  23.3 1  4   202    23.5 2  0  170    22.0 2  3   234   22.2 3  0  208   24.4 3  2  194  24 .7 3  3   204  24.9   I wish to remove all the measurements at time point 0 and convert them to a baseline variable as follows;    ID  time  Y 

Hello, I am trying to test some results I have for significance. It has been recommended that I use R and I am completely new to this. Set-up: Groups: two groups of 8 subjects (16 total) Two conditions: alert and passive Measurements: responses for three different stimuli (A, B, and C) measured in each condition Experiment: Testing the order of conditions Group one: Alert A, B

? Hallo, which function can i use to do (baseline) logistic regression + goodness of fit tests? so far i found: # logistic on binary data lrm combined with resid(model,'gof') # logistic on binary data glm with no gof-test # baseline logit on binary data

I am pretty pleased with baselines I fit to chromatograms using the runquantile() function in caTools(v1.6) when its probs parameter is set to 0.2 and its k parameter to ~1/20th of n (e.g., k ~ 225 for n ~ 4500, where n is time series length). This ignores occasional low- side outliers, and, after baseline subtraction, I can re-adjust any negative values to zero. But runquantile's

Hallo! I have two groups (placebo/verum), every subject is measured at 5 times, the first time t0 is the baseline measurement, t1 to t4 are the measurements after applying the medication (placebo or verum). The question is, if there is a significant difference in the two groups and how large the differnce is (95% confidence intervals). Let me give sample data # Data

Dear all, I am confused with the output of survfit.coxph. Someone said that the survival given by summary(survfit.coxph) is the baseline survival S_0, but some said that is the survival S=S_0^exp{beta*x}. Which one is correct? By the way, if I use "newdata=" in the survfit, does that mean the survival is estimated by the value of covariates in the new data frame? Thank you very much!

Hello everybody. First of all, I would like to present myself. I'm a french student in public health and I like statistics though I'm not that good in mathematics (but I try to catch up). I've discovered R recently while trying to find a statistical program in order to avoid rebooting my computer under windows when I need to do some statistical work. And here is my first question.