similar to: lmer applied to a wellknown (?) example

Hi, I''m trying to understand the lme output and procedure. I''m using the Crawley''s book. I''m try to analyse the rats example take from Sokal and Rohlf (1995). I make a nested analysis using aov following the book. > summary(rats) Glycogen Treatment Rat Liver Min. :125.0 Min. :1 Min. :1.0 Min. :1 1st Qu.:135.8

Hi All, I would like to ask a question on fixed and random effecti in lme. I am fiddlying around Mick Crawley dataset "rats" : http://www.bio.ic.ac.uk/research/mjcraw/statcomp/data/ The advantage is that most work is already done in Crawley's book (page 361 onwards) so I can check what I am doing. I am tryg to reproduce the nested analysis on page 368:

Ronaldo, Further to my previous posting on your Glycogen nested aov model. Having read Douglas Bates' response and Reflected on his lmer analysis output of your aov nested model example as given.The Glycogen treatment has to be a Fixed Effect.If a 'treatment' isn't a Fixed Effect what is ? If Douglas Bates' lmer model is modified to treat Glycogen Treatment as a purely

Your response nicely clarifies a question that I've had for a long time, but which I've dealt with by giving each subject a unique label. Unless I'm missing something, both techniques should work as the toy example below gives exactly the same output in all 3 cases below (forgetting about the convergence problem). Would there be a reason to prefer labeling the levels one way or

Dear R-users, I am trying to analyse the data of the box 10.5 in the Biometry from Sokal and Rohlf (2001) using R. This is a three-level nested anova with equal sample size : 3 different treatments are compared ; 2 rats (coded 1 or 2) / treatment are studied ; 3 preparations (coded 1, 2 or 3) / rats are available ; 2 readings of the glycogen content / preparations are realised. Treatment is

Hello list, I'm trying to figure out how exactly the specification of nested random effects works in the lmer function of lme4. To give a concrete example, consider the rat-liver dataset from the R book (rats.txt from: http://www.bio.ic.ac.uk/research/mjcraw/therbook/data/ ). Crawley suggests to analyze this data in the following way: library(lme4) attach(rats) Treatment <-

Hi, I'm reading van Belle et al "Biostatistics" and trying to run a cox test using a dataset from: http://faculty.washington.edu/~heagerty/Books/Biostatistics/chapter16.html (Primary Biliary Cirrhosis data link at top of the page), I'm using the following code: --------------- start of code library(survival) liver <-

Hi! How to calculate the correct SE of mean in a nested or spliplot anova? Nested example: --------------------- m <- aov(Glycogen~Treatment+Error(Treatment/Rat/Liver)) > m Call: aov(formula = Glycogen ~ Treatment + Error(Treatment/Rat/Liver)) Grand Mean: 142.2222 Stratum 1: Treatment Terms: Treatment Sum of Squares 1557.556 Deg. of Freedom 2 Estimated

Hi, I've been doing an experiment, measuring the dead-zone-diameters of bacteria, when they've been grown with paper diffusion disks of antimicrobial. There are two groups, or treatments - one is bacteria that have been cultured in said antimicrobial for the past year, the other group is of the same species, but lab stock and has not gone had any prior contact with the antimicrobial.

Hi, I have two doubts about the nested aov output. 1) I have this: > anova.ratos <- aov(Glicogenio~Tratamento+Error(Tratamento/Rato/Figado)) > summary(anova.ratos) Error: Tratamento Df Sum Sq Mean Sq Tratamento 2 1557.56 778.78 Error: Tratamento:Rato Df Sum Sq Mean Sq F value Pr(>F) Residuals 3 797.67 265.89 Error: Tratamento:Rato:Figado

Hi, I make this model using lme m.lme <- lme(Glycogen~Treatment,random=~1|rTrt/Liver) How to make this using lmer? I try > m.lmer <- lmer(Glycogen~Treatment+(1|rTrt/Liver)) Erro em lmer(Glycogen ~ Treatment + (1 | rTrt/Liver)) : entry 0 in matrix[0,0] has row 2147483647 and column 2147483647 Al??m disso: Mensagem de aviso: / not meaningful for factors in: Ops.factor(rTrt, Liver)

I have a function that does some plotting. I then add lines to the plot. If executed one line at a time, there is not a problem. If I execute the function, though, I get: Error in ans[[1]] : subscript out of bounds This always occurs after the second lines command, and doesn't happen with all of my data points (some do not have errors). Any ideas? Thanks, Sean

Hello all! I am once again analyzing patient survival data with chronic liver disease. The severity of the liver disease is given by a number which is continuously variable. I have referred to this number as "meld"--model for end stage liver disease--which is the result of a mathematical calculation on underlying laboratory values. So, for example, I can generate a Kaplan-Meier plot

Hi everybody: I?m trying to rewrite some routines originally written for SAS?s PROC NLMIXED into LME4's glmer. These examples came from a paper by Nelson et al. (Use of the Probability Integral Transformation to Fit Nonlinear Mixed-Models with Nonnormal Random Effects - 2006). Firstly the authors fit a Poisson model with canonical link and a single normal random effect bi ~ N(0;Sigma^2).The

Hello, I am just a beginner of R 1.9.0. I try to construct a predictive score for the development of liver cancer in cirrhotic patients. So dependant variable is binanry (cancer yes or no). Independant variables are biological data. The aim is to find out a cut-off value which differentiate (theoratically) from normal to pathological state for each biological data. How can I step in procedue to

Dear R-listers, Does anybody know what is the correct source of "rats" dataset in survival package? The help gives the following information: Rat data from survival5 Description: 48 rats were injected with a carcinogen, and then randomized to either drug or placebo. The number of tumors ranges from 0 to 13; all rats were censored at 6 months after randomization.

Hi, I have a question about how to do covariate adjustment. I have two sets of 'gene expression' data. They are from two different tissue types, 'liver' and 'brain', respectively. The purpose of my analysis is to compare the pattern of the whole genome 'gene expression' between the two tissue types. I have 'age' and 'sex' as covariates. Since

Hi, I am doing an analysis to see if these is tissue specific effects on the gene expression data . Our data were collected from 6 different labs (batch effects). lab 1 has tissue type 1 and tissue type 2, lab 2 has tissue 3, 4,5,6. The other labs has one tissue type each. The 'sample' data is as below:

Hi Dear all, I have some gene expression data samples from different tissue types ----------------------------------------------- - 120 samples from blood (B) - 20 samples from Liver (L) - 15 samples from Kidney (K) - 6 samples from heart (H) ----------------------------------------------- All the samples are from different individuals, so there are in total 161 individuals from which the DNA was

Dear all, I wish to thank Christoph Buser and John Wilkinson for their input, and especially John his examples and for for pointing me to the thread 'Doubt about nested aov output' where the rat-example was hiding...: