similar to: linkage disequilibrium

Dear all, I need to read an ASCII file with diffent length lines. This is what is contained in the file gene.txt: 1st line ID description snp_id genotype 2nd line 10003 Low rs152240 3rd line 10003 Moderate rs189011 TC 4th line 10004 Conservative rs152240 GC 5th line 10004 Bad rs154354 6th line 10013 Bad rs152240 7th line 10019 Conservative rs152240 AC etc... This is what I would like to obtain

Dear all, I have a surprising problem with the representation of frequencies in a histogram. Consider, for example, the R code: b<-rnorm(2000,3.5,0.3) hist(b,freq=F) When I plotted the histogram, I expected that values in the y-axis (the probability) varied between 0 and 1. Instead, they varied within the range 0-1.3. Have you got any suggestion for obtaining a correct graph with

Dear all, is there a automatic method to obtain Odds Ratio estimates and their confidence intervals from a GLM Logistic model? Thanks Cristian ============================================= Cristian Pattaro ============================================= Unit of Epidemiology & Medical Statistics Department of Medicines and Public Health University of Verona cristian@biometria.univr.it

Hi, Anybody knows a function that can fit haplotype data to a Cox model. I've been searching it in the web without succeed. I use "haplo.stats" package, but unfortunatelly it's not possible to analyse survival data, amb I right?. Thanks in advance. Isaac Subirana (isubirana@imim.es) [[alternative HTML version deleted]]

Hi! How can I fill with colors a portion of a graph (e.g.: I want fill in red the area within two confidence intervals)? Thank you very much Cristian ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Cristian Pattaro ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Unit of Epidemiology & Medical Statistics University of Verona Tel +39 045 8027668 fax +39 045 505357 cristian at biometria.univr.it

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Does anyone know if the sib TDT has been implemented in R 1. Spielman, R.S., and Ewens, W.J. (1998) A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet 62, 450-458 -- Farrel Buchinsky, MD Pediatric Otolaryngologist Allegheny General Hospital Pittsburgh, PA

Dear R helpers, I am trying to test for linkage disequilibrium (LD) in R between all pairs of loci. Importantly, my loci are microsatellites and have up to 30 alleles per locus. Do you know of any R packages that can either (1) calculate measures of LD directly or (2) test for the presence of LD within a statistical framework? Every package I have run across seems to be only able to handle

I am involved in a study where, as in most of life, men demonstrate themselves to be recalcitrant. So while we have many probands and most of their mothers we only have about 50% of the trios being complete. I have been running tdt and trio.types. It appears as if it is ignoring the duos. Sometimes a duo can be informative. For instance Father ..missing Mother 1/2 Proband 1/1 This duo shows that

Hi, My query is regarding permutation test and reshuffling of genotype/phenotype data I have been using the haplo.stats package of R. for haplotype analysis and I would like to perform an analysis which I'm requesting your advice. I have a data set of individuals genotyped for 12 SNP and a dichotomous phenotype. At first, I have tested each of those SNP independently in order to bypass

Hi , is it possible to calculate ld-measures D, D', r and perhaps corresponding p-values with r IF THE PHASE IS KNOWN? The genetics - package provides the LD function only for ambigious phase. Thank you very much Bettina Kulle

Hi all, I've been looking in R for an EM algorithm adjusted for multiple-locus haplotypes frequencies, but failed in 100%. Has anyone heard of anything of this kind in R? Thanks in advance, Marcin

Dear list, I am trying to write a package for simulating meioses in R. We defined a class 'haplotype' which contains the basic units of our simulation: setClass("haplotype",representation(snp = "numeric",qtl = "list", hID = "numeric",phID0 = "numeric",phID1 = "numeric"),

I see something new and unexpected here. > update.packages() trying URL `http://cran.r-project.org/src/contrib/PACKAGES' Content type `text/plain; charset=iso-8859-1' length 163467 bytes opened URL .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ......... downloaded

Hi Cristian, I don't know about a R routine for exact CIs, but I found a function called "ageadjust" using a gamma distribution approximation some time ago -take a look at http://medepi.org/epitools/rfunctions/index.html. That Webpage seems a bit outdated now, but the calculations given in the ageadjust functions should still work, I think. Maybe this helps; regards Heinrich.

Dear R mailing list, I have a dataset with genotypes from trios and I would like to infer haplotypes for each mother, father and child. The package that I could find that can do this is tdthap. But when the mother is homozygous (e.g., 2/2) the haplotype is called as not possible to infer (0); I would prefer for it to call the genotype (2). From what I understand it is doing what I would like

Hi! After installing R 2.0.0, I have problem with the "help.search" as below: > help.search("table") Error in help.search("table") : could not find package 'file23525' > help.search("mean") Error in help.search("mean") : could not find package 'file23525' I have had the same problem with other request... What is

Dear friends - a couple of papers in PNAS (lastly:framework for making better predictions by directly estimating variables' predictivity, Lo et al PNAS 2016; 113:14277-14282) have focused interest on mapping complex traits to multiple loci spread all over the genome. I have been around on the relevant taskview(s) I hope but fail to see that the backward haplotype transmission association

Hello, I want to know if there are some functions or packages to solve differential and integral equation using R. Thanks. Shao chunxuan. [[alternative HTML version deleted]]

We have R 2.2.1 installed on a Linux cluster that seems to have problems loading either of our shared object libraries for packages. This seems to be happening on both local and global versions of packages that we install. However, we have only noticed this problem in the past 3 months on this R installation, whereas some users had success before then. It could be that something on our system