similar to: how to calculate predicted probability of Cox model

Hello everybody. First of all, I would like to present myself. I'm a french student in public health and I like statistics though I'm not that good in mathematics (but I try to catch up). I've discovered R recently while trying to find a statistical program in order to avoid rebooting my computer under windows when I need to do some statistical work. And here is my first question.

>Hello, I am hoping for assistance in regards to examining the contribution of stratified variables in a cox regression. A previous post by Terry Therneau noted that "That is the point of a strata; you are declaring a variable to NOT be proportional hazards, and thus there is no single "hazard ratio" that describes it". Given this purpose of stratification, in the

Dear all, Is there a way to calculate the non-cumulative hazard (instantaneous hazard), which is the product of baseline hazard and exp{beta*covariate} ? I knew in survfit, we can get the estimator of cumulative baseline hazard, but how can we get the non-cumulative one? Thank you very much! Koshihaku -- View this message in context:

Dear all, I am trying to find a suitable R-function for parametric proportional hazard regressions. The package survival contains the coxph() function which performs a Cox regression which leaves the base hazard unspecified, i.e. it is a semi-parametric method. The package Design contains the function pphsm() which is good for parametric proportional hazard regressions when the underlying base

Hi everyone. There's been several threads on baseline hazard in Cox model but I think they were all on cumulative baseline hazard, for instance http://tolstoy.newcastle.edu.au/R/help/01a/0464.html http://tolstoy.newcastle.edu.au/R/help/01a/0436.html "basehaz" in package survival seems to do a cumulative hazard. extract from the basehaz function: sfit <- survfit(fit) H

I would like to be able to construct hazard rates (or unconditional death prob) for many subjects from a given survfit. This will involve adjusting the ( n.event/n.risk) with (coxph object )$linear.predictors I must be having another silly day as I cannot reproduce the linear predictor: fit <- coxph(Surv(futime, fustat) ~ age, data = ovarian) fit$linear.predictors[1] [1] 2.612756

Dear R-users, I am checking the proportional hazard assumption of a cox model for a given covariate, let say Z1, after adjusting for other relavent covariates in the model. To this end, I fitted cox model stratified on the discrete values of Z1 and try to get beslow estimator for the baseline cumulative hazard function (H(t)) in each stratum. As far as i know, if the proportionality assumption

Hello, coxph does not use any information that are in the dataset between event times (or "death times") , since computation only occurs at event times. For instance, removing observations when there is no event at that time in the whole dataset does not change the results: > set.seed(1) > data <- as.data.frame(cbind(start=c(1:5,1:5,1:4),stop=c(2:6,2:6,2:5),status=c(rep(

Hi, I was reading a paper published in JCO "Prediction of risk of distant recurrence using 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study" (ICO 2010 28: 1829). The author uses a method to estimate the 9-year risk of distant recurrence as a function of continuous recurrence

Dear R-users, I would like to determine the probability of event at specific time using cox model fit. On the development sample data I am able to get the probability of a event at time point(t). I need probability score of a event at specific time, using scoring scoring dataset which will have only covariates and not the response variables. Here is the sample code: n = 1000 beta1 = 2; beta2 =

Hi, How can I specify a Cox proportional hazards model with a covariate which i believe its strength on survival changes/diminishes with time? The value of the covariate was only recorded once at the beginning of the study for each individual (e.g. at the diagnosis of the disease), so I do not have the time course data of the covariate for any given individual. For example, I want to state at the

Hello , I am hoping for some advice regarding obtaining the values for the hazard function in a cox regression that I have undertaken. I have a model in the following form, analysed with the package survival (v. 2.34-1) and a log-log plot obtained using Design (v. 2.1-2). For two variables, the lines in the survival curves crossed. The statistician I been obtaining advice from (who does not

Dear All, I'm having just a little terminology problem, relating the language used in the Hosmer and Lemeshow text on Applied Survival Analysis to that of the help that comes with the survival package. I am trying to back out the values for the baseline hazard, h_o(t_i), for each event time or observation time. Now survfit(fit)$surv gives me the value of the survival function, S(t_i|X_i,B),

Hi I am estimating the following coxph function with stratification and frailty?where each person had multiple events. m<-coxph(Surv(dtime1,status1)~gender+cage+uplf+strata(enum)+frailty(id),xmodel) ? > head(xmodel) id enum dtime status gender cage uplf 1 1008666 1 2259.1412037 1 MA 0.000 0 2 1008666 2 36.7495023 1 MA 2259.141 0 3 1008666

I am calculating cox propotional hazards models with the coxph function from the survival package. My data relates to failure of various types of endovascular interventions. I can successfully obtain the LR, Wald, and Score test p-values from the coxph.object, as well as the hazard ratio as follows: formula.obj = Surv(days, status) ~ type coxph.model = coxph(formula.obj, df) fit =

My question is, how to compute hazard function(H(t)) after building the coxph model. I even aware of the terminology that differs from hazard function(H(t)) and the hazard rate(h(t)). Here onward I wish to calculate both. Here what I have done in two different methods; ##########################################################################################

I have a very general question about what the centering option in basehaz does to factors. (basehaz computes the baseline cumulative hazard for a coxph object using the Breslow estimator). Lets say I'm interested in a survival model with two (dichotomous) factors and a continuous covariate. Variable Possible Values Factor1 0 or 1 Factor2 0 or 1

I would like to extract predicted failure times from a coxph model in library(survival). However, none of the prediction options ("lp", "risk", "expected", "terms") seem to bear any relationship to failure time. Perhaps I am asking the wrong question, but can coxph provide predicted failure times? Thanks, Dan Bebber Department of Plant Sciences University

Hi, I'm going crazy trying to plot a quite simple graph. i need to plot estimated hazard rate from a cox model. supposing the model i like this: coxPhMod=coxph(Surv(TIME, EV) ~ AGE+A+B+strata(C) data=data) with 4 level for C. how can i obtain a graph with 4 estimated (better smoothed) hazard curve (base-line hazard + 3 proportional) to highlight the effect of C. thanks!! laudan [[alternative

Hi all, Is there an equivalent to predict(...,type="linear") of a Proportional hazard model for a Cox model instead? For example, the Figure 13.12 in MASS (p384) is produced by: (aids.ps <- survreg(Surv(survtime + 0.9, status) ~ state + T.categ + pspline(age, df=6), data = Aidsp)) zz <- predict(aids.ps, data.frame(state = factor(rep("NSW", 83), levels =