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...team for more information." R did not close down after this but was hung up with the hourglass mouse symbol. I've attached a text file with some Y values in it. I've been able to reproduce the error message using the following commands: Y = as.matrix(read.table("C:\\folderpath\\Y_example.txt", header=T)) X=matrix(rnorm(100*20),100,20) example = glmnet(X,Y,family="binomial") If anyone can explain what this error means, or why glmnet would suddently stop working, I would appreciate your insight! Thanks, -- Katherine Fitzgerald PhD Candidate Department of Biology S...