search for: wildtype

HI everyone, I'm plotting a histogram in R and within that histogram i need to demonstrate the percentage of another variable (Percentage of MutStatus) within the bins plotted inthe histogram....I don't know how to do that! Data:Validation_Status Mutation_Status TvarRatio Wildtype None 0.08 Wildtype None 0.08 Wildtype None 0.08 Wildtype None 0.08 Wildtype None 0.080139373 Wildtype None 0.080152672 Wildtype None 0.080213904 Wildtype None 0.080357143 Wildtype None 0.080357143 Wildtype None 0.080357143 Wildtype None 0.08045977 Wildtype None 0.1 Wildtype LOH 0.1 Wildtype None 0....

...totally confused by the many R packages available to do such analysis. Here is my case: I've got a list of genes, and a number of case-control population pairs, and for each population and gene, the various genotypes that have been found. I've got both aggregate data (ex. gene1: homozygote wildtype: 201, heterozygote mutation carrier: 34, homozygote mutation carrier: 5) and per-gene data (i.e. for gene1 a list of e.g. "V/V", "V/I", "II" etc). The question asked is whether there is a difference in the mutation pattern between the case and the control groups influ...

...multiple tests are applied. My questions are: 1) what would be the right way to use R to do and report a simple sign test on this sort of data (paired samples, non-normal, high-inter experiment variability). 2) What is the best way to plot this and how to do it? I was thinking of having each (wildtype-mutant) experiment pair as the ends of line segments with different colors or line-types for each gene-chromatintype combination. I know this is a standard kind of plot but I can't figure out how to do it in R. 3) What is the best way to input this data? A 4d array with virus type (wild ty...

...ied). My questions are: 1) Is there a good way within R to do and report a simple sign test on this sort of data (paired samples, non-normal, high-inter experiment variability)? 2) What would be a good way to plot this sort of noisy data (and how to do it in R)? I was thinking of having each (wildtype-mutant) experiment pair as the ends of line segments with different colors or line-types for each gene-chromatin type combination. I know this is a standard kind of plot but I can't figure out how to do it in R. 3) What is the best way to input this data? A 4d array with virus type (wild t...