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Hi All: OK, this is probably a stupid thing to do but....... Say I have 706 controls and 6 treatments, and want to do a basic two-sample permutation test. I could do a monte carlo approximation but instead want to use perm.test. Now it happens that my data is counts with > unique(x) [1] 1 2 > unique(y) [1] 1 2 5 3 10 9 7 4 6 11 8 23 18 30 16 29 42 so there aren't that many