search for: washout

...is before, and never got a reply (in other cases, the response was within hours). I also checked the S-list, where several similar enquiries of other people are orphaned. We have a cross-over design, where patient are treated two weeks with placebo, two weeks with a drug ("verum"), and a washout phase in between. For each phase, there is ONE number (let's call it "glucose level") describing the treatment effect. Blind treatement sequence is Seq=1 for placebo/verum, Seq=2 for verum/placebo. In Pinheiro/Bates, cross-over trials are mentioned on page 107, but the parameter &quo...