Displaying 1 result from an estimated 1 matches for "twocompmodel".
2012 Feb 05
1
Covariate model in nlme
Dear R users,
I am using nlme to fit a pharmacokinetic model. The base model is
parameterized in terms of CL, V1, V2 and Q.
basemodel<-nlme(Conc ~TwoCompModel(CL,Q,V1,V2,Time,ID),
data = data2, fixed=list(CL+Q+V1+V2~1),
random = pdDiag(CL+V1+V2~1),
start=c(CL=log(20),Q=log(252),V1=log(24.9),V2=log(120)),
control=list(returnObject=TRUE,msVerbose=TRUE,
msMaxIter=20,pnlsMaxIter=20,pnlsTol=1),
verbose=TRUE).
Now, I want to include covariates (age and weight...