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...o get it to work for me. The error I am getting in R is : Error in seek(s) : no applicable method for "seek" Is this the best way to import S-Plus datasets or is there another suggestion that I could try? My data set is 284 variables with 1461rows. Thank-you for your help in advance, Trudi

Hi R-help folks, I have been doing some single SNP association work using snpMatrix. This works well, but produces a lot of false positives, because of population structure in my data. I would like to correct the p-values (which snpMatrix gives me) for population structure, possibly using principle component analysis (PCA). My data is complicated, so here's a simple example of what