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...like to run it on contains n=6000. If it is a limitation, does anyone know of any other ways to do this that would accommodate a larger dataset (ideally with generalized cross validation)? Thanks! -guy33 -- View this message in context: http://r.789695.n4.nabble.com/Fitting-spline-using-Pspline-tp3559202p3559202.html Sent from the R help mailing list archive at Nabble.com.