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Hi, I have a Dataframe. A B C D 0.1 0.7 0.9 0.8 0.20 0.60 0.80 0.70 0.40 0.80 0.70 0.76 I need a resultant dataframe (A-B) (C-D) -0.6 0.1 -0.40 0.1 -0.40 -0.06 Any suggestion would be of a great help Thanks Ramya -- View this message in context: http://r.789695.n4.nabble.com/Finding-a-Diff-within-a-Dataframe-columns-tp3247943p3247943.html Sent from