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...and the t-student distribution is not defined for negative degrees of freedom. Is there some way to calculate the p-value in the ?large p, small n? problem? Thank you all in advance. -- View this message in context: http://www.nabble.com/Large-p%2C-small-n.-Impossible-to-calculate-the-p-value-tp25295288p25295288.html Sent from the R help mailing list archive at Nabble.com.