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survival
2011 Jan 07
2
survval analysis microarray expression data
For any given pre-specified gene or short list of genes, yes the Cox
model works fine. Two important caveats:
1. Remeber the rule of thumb for a Cox model of 20 events per variable
(not n=20). Many microarray studies will have very marginal sample
size.
2. If you are looking at many genes then a completely different strategy
is required. There is a large and growing literature; I like Newton