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Hi, I am having difficulties estimating the parameters of a HMM using the HMM package. I have simulated a sequence of observations from a known HMM. When I estimate the parameters of a HMM using these simulated observations the parameters are not at all close to the known ones. I realise the estimated parameters are not going to be exactly the same as the known/true parameters, but these are

Hi,     I want to use segChrom() method in tilingArray package. For that I need to create a probeAnno object. I could not find much much info by ?probeAnno. I need help in creating  probeAnno object. Snap shot of the file(.txt): chr1 2500014 2500038 + 0.232689943122845 chr1 2500039 2500063 + 2.60502410304227 chr1 2500062 2500086 + 0.0756595313279895 chr1 2500080 2500104 + 0.78574617788405 chr1