Displaying 1 result from an estimated 1 matches for "startextra".
2008 May 02
0
Adaptive design code
...nd( (0.5*(n.0+n.a)/t.A)*(new.tA - t.A) )
nextra.a <- round( (0.5*(n.0+n.a)/t.A)*(new.tA - t.A) )
# final sample size = original sample plus the extra sample
final.size[i] <- nextra.0 + nextra.a + n.0 + n.a
#generate start times for additional patients
startextra.0<-runif(nextra.0,t.A,new.tA)
startextra.a<-runif(nextra.a,t.A,new.tA)
#generate additional sample
yextra.0<- startextra.0 + rexp(nextra.0,(log(2)/med.0))
yextra.a<- startextra.a + rexp(nextra.a,(log(2)/med.a))
# Determine when k is reached (its t...