search for: spendingfunction

....0346????????2? 1.061 1.82??? 0.0346 0.0154????Total??????????????????????0.0500 ?++alpha spending:Pocockboundary.*Sample size ratio compared to fixed design with no interim?Can anyone share some light whether the above analysis is stillvalid? Or for unequal spacing, I have to use Lan-Demet?s error spendingfunction approximations??Thank you, [[alternative HTML version deleted]]

....0346 2 1.061 1.82 0.0346 0.0154 Total 0.0500 ++alpha spending:Pocockboundary.*Sample size ratio compared to fixed design with no interim Can anyone share some light whether the above analysis is stillvalid? Or for unequal spacing, I have to use Lan-Demet?s error spendingfunction approximations? Thank you, > [[alternative HTML version deleted]] > Your example code is a complete mess. Do NOT post in html. This is a plain text mailing list. Read the Posting Guide (https://www.r-project.org/posting-guide.html). Berend Hasselman] > ________________________________...

....0346? ? ? ? 2? 1.061 1.82? ? 0.0346 0.0154? ? Total? ? ? ? ? ? ? ? ? ? ? 0.0500? ++alpha spending:Pocockboundary.*Sample size ratio compared to fixed design with no interim Can anyone share some light whether the above analysis is stillvalid? Or for unequal spacing, I have to use Lan-Demet?s error spendingfunction approximations? Thank you, > ??? [[alternative HTML version deleted]] > Your example code is a complete mess. Do NOT post in html. This is a plain text mailing list. Read the Posting Guide (https://www.r-project.org/posting-guide.html). Berend Hasselman] > _____________________________...

...1 1.82? ? 0.0346 0.0154? ? >Total? ? ? ? ? ? ? ? ? ? ? 0.0500? ++alpha >spending:Pocockboundary.*Sample size ratio compared to fixed design >with no interim Can anyone share some light whether the above analysis >is stillvalid? Or for unequal spacing, I have to use Lan-Demet?s error >spendingfunction approximations? Thank you, >> ??? [[alternative HTML version deleted]] >> > >Your example code is a complete mess. >Do NOT post in html. This is a plain text mailing list. >Read the Posting Guide (https://www.r-project.org/posting-guide.html). > >Berend Hasselman] &gt...