search for: seuratobject

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2023 Aug 06
3
A demonstrated shortcoming of the R package management system
...t reproduction is by saving the code snippet below in the current directory as eg 'matrixIssue.R' and have it run in a container as docker run --rm -ti -v `pwd`:/mnt rocker/r2u Rscript /mnt/matrixIssue.R This runs in under two minutes, first installing the older Matrix, next installs SeuratObject, and then by removing the older Matrix making the (already installed) current Matrix version the default. This simulates a package update for Matrix. Which, as the final snippet demonstrates, silently breaks SeuratObject as the cached S4 method Csparse_validate is now missing. So when SeuratObject...