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2010 Apr 29
1
How to estimate the residual SD for each sample separately in mixed-effects model?
...the SDs using b<-VarCorr(c.lme). There: - the 'attr(b$Assay, "stddev")' is the assay-to-assay SD component for each sample (SDaa) - the 'attr(b$Run, "stddev")' is the run-to-run component (SDrr) - the 'attr(b, "sc")' i.e. the residual (SDres), would be the within-run component, but it's a single number for all the samples. * The problem: - how to estimate the 'within-run' component (SDres) for each sample separately, as the two other components? * Solutions tried: - subtracting SDaa and SDrr from total SD - sometime...