search for: qspr

...regarding regression analysis. I would be grateful if someone could point me to papers/literature in statistical regression analysis which give scientific (statistical) foundation for using Y-RANDOMIZATION. Y-RANDOMIZATION is a widely used technique in QSAR community to unsure the robustness of a QSPR (regression) model. It is used after the "best" regression model is selected and to make sure that there are no chance correlations. Here is a short description. The dependent variable vector (Y-vector) is randomly shuffled and a new QSPR (regression) model is fitted using the original in...