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irets
2010 Jan 22
1
Estimate Slope from Boltzmann Model (package: DRC)
...elp
would be appreciated.
This gets me 3/4 of what I need:
DATA:
Dose,Response
0.85,0.0085
0.90,0.0096
0.95,0.0155
1.00,0.2725
1.05,0.3634
1.10,0.3508
1.15,0.5002
1.20,0.8826
1.25,0.7023
1.30,1.7934
1.35,0.7389
CODE:
library( drc )
mydata <- read.csv( file="test.csv", header=T )
drc.preTBS <- drm( response ~ dose, data = mydata, fct= LL.4( names =
c( "Slope", "Lower Limit", "Upper Limit", "ED50") ) )
For the data above, I would expect a slope at ED50 to be about 0.0714
(according to GraphPad). How can I determine the slope at ED50 for a
Bo...