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...is problem. I use R 1.8.0 and Windows XP professional. My computer has a Pentium 4 2.4 with 512 MB memory. Thanks in advance. best regards, Yu-Kang Tu Clinical Research Fellow Leeds Dental Institute University of Leeds ## change scores simulation close.screen(all=TRUE) split.screen(c(3,3)) nitns<-10000 nsims<-100 r<-0.1 param1<-c(1:nitns) param2<-c(1:nitns) param3<-c(1:nitns) param4<-c(1:nitns) param5<-c(1:nitns) param6<-c(1:nitns) param7<-c(1:nitns) param8<-c(1:nitns) param9<-c(1:nitns) param10<-c(1:nitns) param11<-c(1:nitns) param12<-c(1:nitn...