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Hi all, I've posted this question before, but did not get any reply. I post it again here and see if anybody can help. Thank you. I have a nested model with the following effects fixed: treatments random: experiment_date I used lme() to model the data mod1 <- lme(N_cells ~treatments-1, random=~1|experiment_date, method='ML') Then I want to compare all the other treatments to the control (included in the "treatments" in mod1). After a fair amount of searching around, I decided to use glht() from the multcomp package (any other suggestions?). lvl....