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mul_x2
2010 May 18
1
proportion of treatment effect by a surrogate (fitting multivariate survival model)
...rvival model (Lin, Fleming, and De
Gruttola 1997 in Statistics in Medicine). The paper mentioned that
the covariance matrix matches that of the covariance matrix estimator
for the marginal hazard modelling of multiple events data (Wei, Lin,
and Weissfeld 1989 JASA), and is implemented in Lin's MULCOX2, SAS,
and S-plus.
Is this the way to fit such a model in R?
Suppose I have variables: time, delta, treatment, and surrogate.
Should I repeat the dataset (2x) and stack, creating the variables:
time1 (time repeated 2x), delta1 (delta repeated 2x), treatment1 (same
as treatment, but 0's for the...