search for: mtdna

Hi, I want to analyse DNA sequence data (mtDNA) in R as in calculate Fst, Heterozygosity and such summary statistics. Package Adagenet converts the DNA sequence into retaining only retaining the polymorphic sites and then calcuates Fst.. but is there any other way to do this? I mean analyse the DNA sequence as it is.. and calculate the statisti...

...until July 31st 2015 http://www.gagneur.genzentrum.lmu.de Relevant references: Gagneur et al., PLoS Genetics, 2013, Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype Kornblum et al, Nature Genetics, 2013, Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease [[alternative HTML version deleted]]

...thout success. Thanks for help. Best Jordan [[alternative HTML version deleted]] --Forwarded Message Attachment-- From: bluejay948 at gmail.com To: r-help at r-project.org Date: Mon, 23 Aug 2010 12:30:28 +0200 Subject: [R] DNA sequence Fst Hi, I want to analyse DNA sequence data (mtDNA) in R as in calculate Fst, Heterozygosity and such summary statistics. Package Adagenet converts the DNA sequence into retaining only retaining the polymorphic sites and then calcuates Fst.. but is there any other way to do this? I mean analyse the DNA sequence as it is.. and calculate the statisti...