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mt1
2007 Aug 14
0
Limma - 2x2 factorial design matrix
...he effect of interaction, is it refer to both time and treatment refer, which is refer to M9?
Besides that, I can not figure out the second example of design matrix, Mt for Weaver data set in LimmaGUI help file. Is the design matrix looking at the effect of different time point for mutant sample? Mt11 and Mt21 refer to the effect of mutant at day 11 and day 21 alone? What is the logically theory behind to asign 1 or -1 to slides P21WT.P11WT for effect of Mt11 and Mt21? Does it has anything to do with the vector? Or we will subtract it with Wt at both time point in order for us to look at the eff...