search for: motulsky

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2009 Oct 12
0
Non linear fitting of 2 distributions with shared parameters
...tings of 2 different experimental distributions. I use nls() to the fit the 2 distribution and it works pretty well. The statistical comparison of 2 non linear fits is well described in the book "Fitting Models to Biological Data using Linear and Nonlinear Regression" from Harvey Motulsky and Arthur Christopoulos. This test is based on the calculation of an F-value that compares the residuals of 1°) the global fit of both data sets (with one value for each parameter) on one hand, 2°) with the 2 fits of each separate data sets (with thus 2 values for each parameter) on the othe...
2006 Aug 15
2
nls convergence problem
I'm having problems getting nls to agree that convergence has occurred in a toy problem. nls.out never gets defined when there is an error in nls. Reaching the maximum number of iterations is alway an error, so nls.out never gets defined when the maximum number of iterations is reched. >From ?nls.control: tol: A positive numeric value specifying the tolerance level for the