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Position: Bayesian Modeling Statistician at the level of Research Scientist, Senior Scientist or Principal Scientist, depending on experience. MetrumRG is selectively seeking enthusiastic and energetic individuals to join a team of scientists in a unique working environment. As a member of the MetrumRG team, you will participate in the research, development, and application of quantitative data analysis methods in biomedical sciences throu...

...lly. Founded in 2004, Metrum Research Group has worked with over 85 clients on more than 250 projects. Our experience spans R&D efforts for small molecule pharmaceuticals, biologic therapeutics, diagnostics, and medical device/drug-device combinations, across multiple therapeutic areas. See www.metrumrg.com for more information. Please send resume to employment at metrumrg.com, including a brief cover letter in the body of the email. We prefer to hear directly from candidates. No recruiters please. [[alternative HTML version deleted]]

...lly. Founded in 2004, Metrum Research Group has worked with over 85 clients on more than 250 projects. Our experience spans R&D efforts for small molecule pharmaceuticals, biologic therapeutics, diagnostics, and medical device/drug-device combinations, across multiple therapeutic areas. See www.metrumrg.com for more information. Please send resume to employment at metrumrg.com, including a brief cover letter in the body of the email. We prefer to hear directly from candidates. No recruiters please.

...file. As far as I can tell, the dllname-win.def file is a must in this case making sure none of the keywords get exported there. Also: https://access.redhat.com/documentation/en-US/Red_Hat_Enterprise_Linux/4/html/Using_ld_the_GNU_Linker/win32.html -- Kyle Baron Metrum Research Group kyleb at metrumrg.com www.metrumrg.com On Wed, Jul 27, 2016 at 7:47 PM, Kyle Baron <kyleb at metrumrg.com> wrote: > > I am building shared objects on Windows system with BASE as a name in > the shared object. When BASE appears under EXPORTS in tmp.def file, R > CMD SHLIB doesn't succeed. Th...

...search Group has worked with over 100 clients on more than 250 projects. Our experience spans R&D efforts for small molecule pharmaceuticals, biologic therapeutics, diagnostics, and medical device/drug-device combinations, across multiple therapeutic areas. Please send resume to employment at metrumrg.com (mailto:employment at metrumrg.com) , including a brief cover letter in the body of the email. We prefer to hear directly from candidates. No recruiters please. James A. Rogers, Ph.D. Principal Scientist, Statistics Metrum Research Group www.metrumrg.com (http://www.metrumrg.com/)

...Is facet_wrap or facet_grid capable of producing multiple pages of plots and, if so, how? Thanks, Bill William R Gillespie, VP Strategic Modeling & Simulation Metrum Research Group LLC 2 Tunxis Road, Suite 112, Tariffville, CT 06081 Direct & FAX:919-371-2786, Main:860-735-7043 billg at metrumrg.com www.metrumrg.com

r-devel, In a development version of the CRAN package metrumrg, I write ... require(reshape) setGeneric('cast') setOldClass(c('keyed','data.frame')) setMethod('cast','keyed', function ...) The result is satisfactory when sourcing the code directly, but when checking the package (which has 'reshape' as a depende...

Is there a conventional way to test for nested factors? I.e., if 'a' and 'b' are lists of same-length factors, does each level specified by 'a' correspond to exactly one level specified by 'b'? The function below seems to suffice, but I'd be happy to know of a more succinct solution, if it already exists. Thanks, Tim. --- "%nested.in%" <-

...dows platforms (per https://cran.r-project.org/doc/manuals/R-exts.html#Creating-shared-objects) ... it worked but seems that the file needs to be in getwd(), which I'd rather not do. Any insight or advice would be appreciated. Best Regards, Kyle -- Kyle Baron Metrum Research Group kyleb at metrumrg.com www.metrumrg.com sessionInfo() R version 3.3.1 (2016-06-21) Platform: x86_64-w64-mingw32/x64 (64-bit) Running under: Windows Server 2008 R2 x64 (build 7601) Service Pack 1 locale: [1] LC_COLLATE=English_United States.1252 [2] LC_CTYPE=English_United States.1252 [3] LC_MONETARY=English_Unite...

I originally posted on this topic on a different thread: https://stat.ethz.ch/pipermail/r-devel/2016-August/072938.html These sources suggested that a safe practice might be to put double quotes around symbol names in EXPORTS in case the symbol name is the same as a linker keyword: - https://sourceware.org/binutils/docs/ld/Symbols.html#Symbols -

Suppose I have a list of logicals, such as returned by lapply: Theoph$Dose[1] <- NA Theoph$Time[2] <- NA Theoph$conc[3] <- NA lapply(Theoph,is.na) Is there a direct way to execute logical "or" across all vectors? The following gives the desired result, but seems unnecessarily complex. as.logical(apply(do.call("rbind",lapply(Theoph,is.na)),2,"sum"))

Hi. I have a vector of quantiles and a vector of probabilites that, when plotted, look very like the gamma cumulative distribution function. I can guess some shape and scale parameters that give a similar result, but I'd rather let the parameters be estimated. Is there a direct way to do this in R? Thanks, Tim. week <- c(0,5,6,7,9,11,14,19,39) fraction <-

..., or training for R. I am already aware of a number of such companies including (in alphabetical order): BlueReference <http://inference.us> Insightful <http://www.insightful.com> Metrum Institute <http://www.metruminstitute.org> Metrum Research Group, LLC <http://www.metrumrg.com> Random Technologies LLC <http://random-technologies-llc.com> REvolution Computing Inc <http://revolution-computing.com> Statistics.com <http://www.statistics.com> XLSolutions Corporation <http://www.xlsolutions-corp.com> If you are aware of a company that provid...

Hi. I'm trying to find a systematic way to prevent assignment to names of existing functions. I've tried reassigning to the assignment operator, with mixed results. The function definition for "<-" below works as hoped for the demonstrated assignments to a and c. However, for the assignment based on the test function, it appears that the formal argument is not

I see in the archives significant discussion about SAS, CDISC formats etc. for FDA, but no direct suggestion of adding a write.xport method to the foreign package. Are there significant barriers to doing so? [[alternative HTML version deleted]]

Hi. I frequently convert date and time data to and from character representations. I'm frustrated with chron, because 'seconds' are required to create a time object (my input data never has seconds). More importantly, I cannot make chron print the format 12/30/2006 (which my output data requires). I really like the format flexibility of strftime() and strptime(), but of course

Suppose I want to delete everything in my working directory that is not a function. It seems that sapply(ls(),is.function) always returns FALSE, because ls() returns objects of mode character. How do I evaluate is.function(), not on a character string, but on the object that character string represents? Thanks, Tim

Hi. I'm maintaining a package that creates an object that is essentially a classed version of numeric. I updated recently from 2.7.1 to 2.9.0, and merges involving my class suddenly took a huge performance hit. I've traced the problem to something near rank(). From NEWS, it seems rank() etc. changed in 2.8.0. Methods for xtfrm() are supposed to help, but I've had no success. There

CRAN (and crantastic) updates this week New packages ------------ * disclapmix (0.1) Maintainer: Mikkel Meyer Andersen Author(s): Mikkel Meyer Andersen and Poul Svante Eriksen License: GPL-2 http://crantastic.org/packages/disclapmix disclapmix makes inference in a mixture of Discrete Laplace distributions using the EM algorithm. * EstSimPDMP (1.1) Maintainer: Unknown Author(s):

Hi. When I extend "numeric" with S4 and create an instance, I get something that looks and acts like a numeric. When I extend "data.frame" and create an instance, I get a NULL 'core'. Why is this, and can it be fixed? setOldClass(), prototype=, and initialize() don't seem to help. Thanks, Tim ----