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2002 Dec 15
2
Interpretation of hypothesis tests for mixed models
My question concerns the logic behind hypothesis tests for fixed-effect terms in models fitted with lme. Suppose the levels of Subj indicate a grouping structure (k subjects) and Trt is a two-level factor (two treatments) for which there are several (n) responses y from each treatment and subject combination. If one suspects a subject by treatment interaction, either of the following models seem