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...ostly C-based fast cbind() / rbind() functions. As some Bioconductor developers have recently found, these versions of cbind() and rbind() that have been automagically activated by loading the Matrix package can have a detrimental effect in some extreme cases, e.g. when using do.call(cbind, list_of_length_1000) because of the recursion and the many many calls to the S4 generic, each time searching for method dispatch ... For the bioconductor applications and potentially for others using cbind() / rbind() extensively, this can lead to unacceptable performance loss just because loading 'Matrix' cur...