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iruczins
2011 Jan 03
0
Using PCA to correct p-values from snpMatrix
...o correct my p-values (in
single.snp.association) for population structure? In my real data, population
structure is causing a lot of type I errors (false positive SNPs).
I have read of some standalone software that does this sort of thing, for
example EIGENSTRAT:
http://www.biostat.jhsph.edu/~iruczins/teaching/misc/gwas/papers/price2006.pdf
But I'd like to stick to R if possible.
Any advice/comments welcome.