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...nd for such use cases we plan to introduce runtime calls that can return the required shadow address. The ptrtoint introduced by the instrumentation hinder optimizations that are important for OpenCL and other heterogeneous languages which directly or indirectly use address spaces. For example, InferAddressSpace which statically determines the address space of generic addresses, it does not work after seeing ptrtoint as one of the uses. The same applies to any optimization that deals with alias analysis or pointers in general. The hurdle in getting rid of the introduced ptrtoint in instrumentation is t...