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How do you update R on Windows and how do you install your own package with windows interface ? regards, Ghislaine GUIGON Biostatisticienne Plate-forme 2 Puces a ADN INSTITUT PASTEUR 25-28 rue du Dr ROUX 75724 Paris cedex 15 FRANCE tel: (33) (0)1 40 61 86 51 fax: (33) (0)1 45 68 84 06

...s "character" is sealed; new superclasses can not be defined, except by setClassUnion Error in getClass(Class, where = topenv(parent.frame())) : "MIAME" is not a defined class Error in library(affy) : .First.lib failed Is someone still have this problem ? Ghislaine GUIGON Biostatisticienne

...annot stat: No such file or di rectory tar: maanova: Cannot stat: No such file or directory tar: Error exit delayed from previous errors maanova_0.91-3.tar: No such file or directory Is someone still have same problem ? Rtools are installed. Thanks for answers, Ghislaine GUIGON Biostatisticienne Plate-forme 2 Puces a ADN INSTITUT PASTEUR 25-28 rue du Dr ROUX 75724 Paris cedex 15 FRANCE tel: (33) (0)1 40 61 86 51 fax: (33) (0)1 45 68 84 06

I'm tryng to use loess normalization function based on externals controls (like MSP) as in Yang et al.; 2002 paper. I work with bioconductor marrayNorm package. I identified my controls in the maControls structure of marrayLayout as a vector of 0 and 1. Is someone still use it ? for the moment I just have ... test <- maNormMain(manip.raw, f.loc = list(maNormLoess(x="maA",