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...erence between I use (-1, 1) to represent the lower and higher levels and I use (5000, 10000) as the real levels? 3) how can I extract the coefficients after analysis, I mean can I write the coefficients as a vector? 4) how can I call R function from C code, for example, can I call lm(...) from C functiomns? 5) after experiment designs, we can analyse which factors have big effects, can we construct in R a response surface so that we can optimise the levels of the factors by maxmising the response surface, can you advise me how to do that in R? 6) if the number of factors is over 1000, is it possib...