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we have some initial data from our field sampling. From the means and variances, we see your sampling field is much heterogeneous (not uniform). We are looking for a "R" program for sampling size determination. Right now, we are not good enough to write a whole "R" program, so please help. [[alternative HTML version deleted]]

Hello list I have a theoretical differential equation model (two coupled differential equations) describing the acidification of dairy cultures in milk: dX/dt = f(H, param)*X dH/dt = g(param)*dX/dt pH = -log10(H) I also have actual data of the same. I would like to estimate the parameters of the theoretical model from real data, but don't know how to go about it in R (I'm fairly new